WELCOME TO QUALITY BIORESOURCES, INC
Freeze drying, or lyophilization, is a method of removing water from various materials. Lyophilization of enzymes, antibodies, and sensitive biological materials is the method of choice for extending the shelf life of these products and preserving their biological activity. By preparing dilute solutions of biological materials, dispensing the solution in tubes or vials, and then lyophilization them it is possible to reproducibly distribute minute quantities of reagents into thousands of tubes with minimal tube-to-tube variation. Quality Bioresources, Inc. will dispense and freeze dry your materials, employing strict controls at each stage to assure that the final product is within your lyophilization specifications.
QBI currently has three bulk lyophilization units with plans to aquire two more in the next few months. Our twin hull bulk lyophilization units have 72 and 84 sq ft, both with ~100L condensor capacity. Both these bulk lyophilization units have backfill and stoppering capabilities and are well suited for serum vials up to 50 mls as well as tray drying. When necessary both can be controlled by a single programer to produce a total shelf space of 156 sq ft. Our pilot scale Virtis has 24 sq. ft. of shelf space and a 50 liter internal condenser. Also fitted with stoppering and back-fill capabilities, the Virtis is ideal for small-scale bulk lyophilization drying and pilot runs.
Quality Bioresources IVD manufacture offers contract liquid filling of your solutions. QBI IVD manufacture has extensive experience in the dispensing of microliter to 100-liter quantities of biological reagents. With a variety of tools to ensure rapid turn-around with minimal vial-to-vial variation, QBI IVD manufacture is equipped to handle your liquid filling needs. For one of our long-term invitro diagnostic customers, QBI routinely fills in excess of 100,000 vials per week. While companies have moved to automated systems, QBI continues filling by hand for a number of reasons. The primary reason is that human operators can do continuous quality control, identifying problems and rejects immediately. Even with such close attention to quality, QBI offers our services at a price that typically rivals even automated IVD manufacture processes.
Quality Bioresources can fulfill all of your lyophilization services and product handling needs from solublization, mixing, dispensing, and lyophilization to packaging and shipping. QBI has lyophilization services of growth media to an international distributor of bacterial, yeast, nematode, and cell culture media for over 5 years and we can do the same for you. We have fast turn around, small and large scale capabilities and can provide custom lyophilization services labels. QBI will warehouse products and drop-ship directly to your customers. The heart of operations at Quality Bioresources rests in our ability to rapidly lyophilize products for our lyophilization services customers.
If specificity of the custom antibody production is important, it is imperative that unique peptide sequences be selected. If the custom antibody production are to be used for ELISA, Immunolocalization, or Immunoprecipitation it is important that the sequences be from a hydrophilic portion of the protein that will be accessible to IgG in solution (i.e. make sure the sequence isn't buried in the core of the native protein). If there are no cysteins in the custom antibody production sequence, it is often advantageous to add a cystein at the N or C terminus to facilitate the coupling of the peptide to the carrier. This approach has the advantage of ensuring that the entire peptide sequence is available in the custom antibody production process.
Quality Bioresources, Inc. is a medical device lyphilization contract manufacturer specializing in custom antibody production and packaging. Our high medical device lyphilization volume, low cost, and rapid turn around has allowed us to maintain long-term relationships with all of our clients. As a cGMP company (we are soon to be a ISO9001company), we take pride in the careful handling and documentation of all of the medical device lyphilization products that enter and leave our facility. We provide a broad range of services and products that will serve as a resource for anyone who uses, produces, or markets medical device lyphilization.
Quality Bioresources, Inc. can fulfill all of your GMP lyophilization product handling needs from solublization, mixing, dispensing, and GMP lyophilization to packaging and shipping. QBI has supplied growth media to an international distributor of bacterial, yeast, nematode, and cell culture media for over 5 years. We can handle GMP lyophilization handling of antibodies from as little as 100 micrograms of antigen. We deal in Antibodies from SDS-PAGE gel slices, inclusion bodies, or peptides and have over 20 years of experience in antibody production. Quality Bioresources, Inc. has a 2600 sq. ft. animal facility for the production of antibodies in a number of host species. We are a USDA registered animal GMP lyophilization facility.
Quality Bioresources in vitro diagnostic manufacture has a wealth of experience in the custom fomulation of powders and solutions for our customers. QBI in vitro diagnostic manufacture has produced custom media, laboratory buffers, laboratory reagents, enzyme conjugates, and other products for various internationally recognized customers. The formulation of various powdered products is an important time saving step for researchers and industrial scientists. QBI in vitro diagnostic manufacture has the capacity to blend up to 70 Kg lots of homogenous, free-flowing powders using our V-blender. Smaller, pilot-scale blending is available using our Mini-V. For larger media requirements, a strategic alliance that gives us access to a 500 Kg V-blender is available through QBI in vitro diagnostic manufacture.